To amend the Public Health Service Act to authorize the Secretary of Health and Human Services to carry out a program of research, training, and investigation related to Down syndrome, and for other purposes.
Analysis under review: This bill has generated analysis that may be too generic or incomplete. Clause-level evidence remains available below.
Summary
What This Bill Does
This bill establishes the INCLUDE Project (INvestigation of Co-occurring conditions across the Lifespan to Understand Down syndromE) at NIH. It authorizes a comprehensive research program studying Down syndrome, including why conditions like Alzheimer's disease and autoimmune disorders are more common in people with Down syndrome.
Who Benefits and How
- Individuals with Down syndrome benefit from expanded clinical trials specifically designed for them and research into treatments for co-occurring conditions
- NIH and medical researchers receive authority and direction to pursue high-risk, high-reward studies on chromosome 21 and Down syndrome
- Pharmaceutical and biotech companies developing treatments for Down syndrome-related conditions gain access to a large study population and clinical trial infrastructure
Who Bears the Burden and How
- NIH must establish and maintain the INCLUDE Project, assemble a large study population, and coordinate with federal agencies
- Federal budget bears the cost of the research program (no specific appropriation amount stated)
Key Provisions
- Establishes research into effects of chromosome 21 on human development
- Requires assembling a large study population of individuals with Down syndrome
- Expands clinical trials inclusive of or designed for individuals with Down syndrome
- Studies why Alzheimer's disease and autoimmune conditions are prevalent in Down syndrome
Evidence Chain:
This summary is generated from the full bill text using AI analysis. Expand "Detailed Analysis" below for identified beneficiaries/burden bearers with clause-level evidence links.
At a Glance
What This Bill Does
Authorizes NIH to establish the INCLUDE Project, a comprehensive research program studying Down syndrome across the lifespan including co-occurring conditions like Alzheimer's disease
Key Policy Areas
Healthcare, Medical Research, Disability Rights
Primary Purpose
Authorizes NIH to establish the INCLUDE Project, a comprehensive research program studying Down syndrome across the lifespan including co-occurring conditions like Alzheimer's disease
Policy Domains
Main Bill
Identified Gains
- Individuals with Down syndrome
- Medical researchers
- Pharmaceutical companies developing Down syndrome treatments
Identified Costs
- National Institutes of Health
Sponsors
Legislative Progress
Passed HouseReceived; read twice and referred to the Committee on Health, …
Additional sponsor: Mr. Trone
Reported with an amendment, committed to the Committee of the …
Mrs. Rodgers of Washington (for herself, Ms. DeGette, Mr. Cole, …
Passed House (inferred from eh version)
Stakeholder Effects
cui bono?How this legislation distributes effects. Mention counts reflect frequency, not effect magnitude.
Clinical trial organizations, Medical researchers studying Down syndrome
Pharmaceutical companies developing Down syndrome treatments
Bill Structure & Actor Mappings
Who is "The Secretary" in each section?
- "the_secretary"
- → Secretary of Health and Human Services
- "director_of_nih"
- → Director of NIH
Key Definitions
Terms defined in this bill
INvestigation of Co-occurring conditions across the Lifespan to Understand Down syndromE Project
We use a combination of our own taxonomy and classification in addition to large language models to assess meaning and potential beneficiaries. High confidence means strong textual evidence. Always verify with the original bill text.
Learn more about our methodology